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Conolidine’s analgesic consequences stem from its conversation with non-opioid pain pathways. Unlike opioids, which bind to µ-opioid receptors during the central nervous system, conolidine modulates alternate molecular targets… Read More

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Even though the opiate receptor depends on G protein coupling for sign transduction, this receptor was observed to make the most of arrestin activation for internalization with the receptor. Or else, the receptor promoted no o… Read More